Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | GPR183 | P32249 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ME2 | P23368 | 1/20 | 0.37 |
| ▸ | ME1 | P48163 | 1/20 | 0.37 |
| ▸ | ME3 | Q16798 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764707 | 0.77 | HSD11B1 (0.55) | HSD11B1GPR183KMT2AMEN1CYP2C9 | |
| SCHEMBL30764735 | 0.75 | HSD11B1 (0.51) | HSD11B1GPR183KMT2AMEN1GFER | |
| SCHEMBL30764705 | 0.73 | EPHX2 (0.45) | HSD11B1GPR183KMT2AMEN1CYP2C19 | |
| SCHEMBL30764715 | 0.73 | HSD11B1 (0.51) | HSD11B1GPR183KMT2AMEN1CYP2C9 | |
| SCHEMBL30764755 | 0.71 | GAA (0.54) | HSD11B1KMT2AMEN1 | |
| SCHEMBL30764763 | 0.71 | HSD11B1 (0.46) | HSD11B1GPR183KMT2ACYP2C9CYP2C19 | |
| SCHEMBL30764734 | 0.71 | KMT2A (0.54) | HSD11B1GPR183KMT2AMEN1GFER | |
| SCHEMBL30764758 | 0.70 | KDM4E (0.59) | HSD11B1GPR183KMT2AMEN1GFER | |
| SCHEMBL27253355 | 0.70 | HSD11B1 (0.62) | HSD11B1GPR183KMT2AMEN1CYP2C9 | |
| SCHEMBL30764713 | 0.70 | HSD11B1 (0.47) | HSD11B1GPR183KMT2AMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568968-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Remynd N.V. (BE) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |