Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764723 | 0.92 | KDM4E (0.46) | EPHX2KDM4EALDH1A1ALOX15HSD11B1 | |
| SCHEMBL30764707 | 0.80 | HSD11B1 (0.55) | KDM4EALDH1A1HSD11B1CYP2C19GFER | |
| SCHEMBL30764745 | 0.75 | SIGMAR1 (0.53) | KDM4EALDH1A1ALOX15HSD11B1CYP2C19 | |
| SCHEMBL30764749 | 0.74 | HSD11B1 (0.49) | HSD11B1CYP2C19GFERATMKCNH2 | |
| SCHEMBL5391243 | 0.74 | CCR8 (0.58) | KDM4EALDH1A1ALOX15HSD11B1CYP2C19 | |
| SCHEMBL30764735 | 0.74 | HSD11B1 (0.51) | ALDH1A1HSD11B1GFERATMMEN1 | |
| SCHEMBL30764758 | 0.73 | KDM4E (0.59) | KDM4EALDH1A1HSD11B1GFERATM | |
| Trifluoroacetic Acid SCHEMBL5434664 | 0.73 | CCR8 (0.52) | KDM4EALDH1A1ALOX15HSD11B1CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL5428442 | 0.73 | CCR8 (0.54) | KDM4EALDH1A1ALOX15HSD11B1PTGDR2 | |
| SCHEMBL30764753 | 0.73 | HSD11B1 (0.46) | HSD11B1CYP2C19GFERATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568968-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Remynd N.V. (BE) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |