Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558554 | 0.83 | NOTUM (0.34) | ALDH1A1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL31558502 | 0.83 | NOTUM (0.34) | ALDH1A1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL31558543 | 0.76 | HSD11B1 (0.35) | ENPP3ENPP1 | |
| SCHEMBL31558466 | 0.75 | ALOX15 (0.40) | HDAC1HDAC8HDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL16088972 | 0.74 | RAB9A (0.40) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL19034289 | 0.74 | RAB9A (0.40) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL14701593 | 0.73 | ALDH1A1 (0.46) | HDAC1HDAC8HDAC6ALDH1A1ENPP3 | |
| SCHEMBL30765890 | 0.71 | PTGS2 (0.40) | ALDH1A1MAPTHPGD | |
| SCHEMBL29472427 | 0.71 | PTGS2 (0.40) | ALDH1A1MAPTHPGD | |
| SCHEMBL28673711 | 0.71 | PTGS2 (0.40) | ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |