Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765931 | 0.87 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNANPSR1JAK2 | |
| SCHEMBL30765941 | 0.87 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNANPSR1JAK2 | |
| SCHEMBL30765758 | 0.87 | L3MBTL1 (0.40) | ALDH1A1KDM4ELMNANPSR1TSHR | |
| SCHEMBL30766068 | 0.84 | GPR139 (0.34) | ALDH1A1KDM4ELMNANPSR1KMT2A | |
| SCHEMBL30765729 | 0.83 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNANPSR1JAK2 | |
| SCHEMBL30765944 | 0.82 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNANPSR1JAK2 | |
| SCHEMBL30765521 | 0.79 | KMT2A (0.38) | ALDH1A1KDM4ELMNANPSR1TSHR | |
| SCHEMBL30765733 | 0.79 | KMT2A (0.36) | ALDH1A1KDM4ELMNANPSR1TSHR | |
| SCHEMBL30765957 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNANPSR1JAK2 | |
| SCHEMBL30765712 | 0.78 | LMNA (0.35) | ALDH1A1KDM4ELMNANPSR1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |