Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31665020 | 0.85 | KIF11 (0.49) | SMN1; SMN2ALDH1A1KDM4ETRPA1POLB | |
| SCHEMBL10762792 | 0.74 | JAK3 (0.49) | SMN1; SMN2ALDH1A1KDM4ETRPA1POLB | |
| SCHEMBL30462004 | 0.73 | KIF11 (0.51) | KDM4EKMT2ACASP3MAOBCYP11B1 | |
| SCHEMBL3387516 | 0.73 | KIF11 (0.51) | KDM4EKMT2ACASP3MAOBCYP11B1 | |
| SCHEMBL29502570 | 0.73 | AGBL2 (0.43) | SMN1; SMN2ALDH1A1KDM4EPOLBRAB9A | |
| Hydrochloric Acid SCHEMBL31453978 | 0.72 | KIF11 (0.50) | KDM4EKMT2ACASP3MAOBCYP11B1 | |
| SCHEMBL2290365 | 0.70 | MAOB (0.57) | ALDH1A1KDM4EMAOB | |
| SCHEMBL6176543 | 0.70 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1KDM4EPOLBRAB9A | |
| SCHEMBL27174339 | 0.69 | TRPV1 (0.41) | ALDH1A1KDM4E | |
| SCHEMBL18370105 | 0.69 | KLKB1 (0.38) | SMN1; SMN2ALDH1A1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568960-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033458-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |