Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31497815 | 0.78 | EPAS1 (0.47) | EPAS1MAPTTLR8TDP1 | |
| SCHEMBL31448472 | 0.76 | EPAS1 (0.51) | EPAS1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31448550 | 0.76 | ALDH1A1 (0.36) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL30772401 | 0.74 | L3MBTL1 (0.35) | EPAS1MAPTALDH1A1TLR8SMN1; SMN2 | |
| SCHEMBL31448485 | 0.74 | MEN1 (0.41) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL31497825 | 0.73 | MAPT (0.42) | EPAS1MAPTALDH1A1LMNATLR8 | |
| SCHEMBL31497857 | 0.73 | EPAS1 (0.43) | EPAS1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30772350 | 0.73 | HSPB1 (0.39) | EPAS1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6197458 | 0.70 | TSHR (0.55) | MEN1KMT2AALDH1A1LMNATDP1 | |
| SCHEMBL103199 | 0.70 | TDP1 (0.53) | MEN1KMT2AMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250361210-A1 | 3,4-DIHYDROQUINOLIN-2(1H)-ONE COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2025-11-27 | — | — | US | disclosed |
| EP-4512801-A1 | 3,4-DIHYDROQUINOLIN-2(1H)-ONE COMPOUND | Kissei Pharmaceutical Co., Ltd. (JP) | 2025-02-26 | — | — | EP | disclosed |
| CN-119343332-A | 3, 4-Dihydro-quinolin-2 (1H) -one compounds | 橘生药品工业株式会社 | 2025-01-21 | — | — | CN | disclosed |
| WO-2024005113-A1 | 3,4-DIHYDROQUINOLIN-2(1H)-ONE COMPOUND | キッセイ薬品工業株式会社 | 2024-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250361210-A1 | 3,4-DIHYDROQUINOLIN-2(1H)-ONE COMPOUND | TSHR, TRHR, GHSR | EPAS1 2277/4885MEN1 90/4885KMT2A 1876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.