Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30778456 | 1.00 | ALDH1A1 (0.39) | ALDH1A1GAASMN1; SMN2LMNAS1PR3 | |
| SCHEMBL882494 | 0.81 | ALDH1A1 (0.37) | ALDH1A1GAASMN1; SMN2LMNAS1PR3 | |
| SCHEMBL1090665 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNACYP3A4CYP2D6SLC6A2 | |
| SCHEMBL3962576 | 0.77 | RPS6KB1 (0.39) | ALDH1A1GAALMNAS1PR3CYP3A4 | |
| SCHEMBL22736030 | 0.77 | CYP11B1 (0.34) | ALDH1A1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL23534220 | 0.77 | NOS3 (0.42) | SMN1; SMN2CYP11B1CYP11B2PIK3CD | |
| SCHEMBL30060434 | 0.77 | NOS3 (0.42) | SMN1; SMN2CYP11B1CYP11B2PIK3CD | |
| SCHEMBL169697 | 0.77 | SMN1; SMN2 (0.36) | ALDH1A1GAASMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL4252351 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL15643867 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP3A4CYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250100995-A1 | CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | CELGENE CORPORATION | 2025-03-27 | — | — | US | disclosed |
| EP-4359406-A1 | CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | Celgene Corporation (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117545752-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 细胞基因公司 | 2024-02-09 | — | — | CN | disclosed |
| WO-2022272053-A1 | CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | CELGENE CORPORATION (US) | 2022-12-29 | — | — | WO | disclosed |
| EP-1732895-B1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2016-11-16 | — | — | EP | disclosed |
| EP-2736900-A1 | SUBSTITUTED HETEROAROMATIC PYRAZOLE-CONTAINING CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2014-06-04 | — | — | EP | disclosed |
| EP-2736882-A1 | SUBSTITUTED HETEROCYCLIC AZA DERIVATIVES | Grünenthal GmbH (DE) | 2014-06-04 | — | — | EP | disclosed |
| CN-103842357-A | Substituted heteroaromatic pyrazole-containing carboxamide and urea compounds as vanilloid receptor ligands | GRUENENTHAL GMBH | 2014-06-04 | — | — | CN | disclosed |
| WO-2013013817-A1 | SUBSTITUTED HETEROCYCLIC AZA DERIVATIVES | Grünenthal GmbH (DE) | 2013-01-31 | — | — | WO | disclosed |
| US-20130029962-A1 | Substituted Heteroaromatic Pyrazole-Containing Carboxamide and Urea Compounds as Vanilloid Receptor Ligands | GRUENENTHAL GMBH (DE) | 2013-01-31 | — | — | US | disclosed |
| US-20100056579-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | US | disclosed |
| CN-101648906-A | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC US | 2010-02-17 | — | — | CN | disclosed |
| US-20080033020-A1 | 3-Pyridinylethylbenzamide Derivatives as Fungicides | BAYER CROPSCIENCE S.A. (FR) | 2008-02-07 | — | — | US | disclosed |
| EP-1773776-A1 | 3-PYRIDINYLETHYLBENZAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2007-04-18 | — | — | EP | disclosed |
| CN-1942442-A | Insecticidal N-substituted sulfenimides | DOW AGROSCIENCES LLC (US) | 2007-04-04 | — | — | CN | disclosed |
| EP-1732895-A2 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | Dow Agrosciences LLC (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2006060029-A2 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2006-06-08 | — | — | WO | disclosed |
| WO-2006008191-A1 | 3-PYRIDINYLETHYLBENZAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2006-01-26 | — | — | WO | disclosed |
| US-20050228027-A1 | Insecticidal N-substituted sulfoximines | CORTEVA AGRISCIENCE LLC | 2005-10-13 | — | — | US | disclosed |
| CN-1091425-A | Heterocyclic neophenan analogs, process for their preparation and their use as pesticides | HOECHST AG (DE) | 1994-08-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056579-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | GSS, STS, SMS | ALDH1A1 3325/4885GAA 4740/4885SMN1; SMN2 253/4885 |
| US-20250100995-A1 | CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | CRBN, AR, ESRRA | ALDH1A1 709/4885GAA 2788/4885SMN1; SMN2 685/4885 |
| US-20080033020-A1 | 3-Pyridinylethylbenzamide Derivatives as Fungicides | CYP1A2, CYP4B1, CYP4F2 | ALDH1A1 642/4885GAA 122/4885SMN1; SMN2 3883/4885 |
| US-20130029962-A1 | Substituted Heteroaromatic Pyrazole-Containing Carboxamide and Urea Compounds as Vanilloid Receptor Ligands | TRPV1, GPR17, TRPV3 | ALDH1A1 3441/4885GAA 2687/4885SMN1; SMN2 4397/4885 |
| US-20050228027-A1 | Insecticidal N-substituted sulfoximines | GSS, STS, SMS | ALDH1A1 3325/4885GAA 4740/4885SMN1; SMN2 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.