Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 3/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782918 | 0.91 | HTR6 (0.37) | BRD4CREBBPOXTRHTR6AVPR1A | |
| SCHEMBL30782874 | 0.87 | CYP11B2 (0.41) | USP30UCHL1GPR119 | |
| SCHEMBL30782865 | 0.79 | UCHL1 (0.38) | HTR6UCHL1HTR2CSLC6A4 | |
| SCHEMBL31664591 | 0.74 | BRD4 (0.36) | BRD4CREBBPHTR2CSLC6A4 | |
| SCHEMBL31664593 | 0.74 | BRD4 (0.36) | BRD4CREBBPHTR2CSLC6A4 | |
| SCHEMBL30782897 | 0.73 | HTR6 (0.38) | HTR6KDM4C | |
| SCHEMBL20700569 | 0.72 | MGLL (0.35) | BRD4CREBBPOXTRUCHL1HTR2C | |
| SCHEMBL22814012 | 0.72 | ADRA2A (0.39) | SLC6A4GPR119 | |
| SCHEMBL31664596 | 0.72 | BRD4 (0.35) | BRD4CREBBPUSP30UCHL1GPR119 | |
| SCHEMBL31664598 | 0.71 | HTR1A (0.38) | BRD4CREBBPOXTRAVPR1AUCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4593954-A1 | COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI Drug Discovery LLC (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073383-A1 | COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI DRUG DISCOVERY LLC (US) | 2024-04-04 | — | — | WO | disclosed |