Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRDM9 | Q9NQV7 | 1/20 | 1.00 |
| ▸ | PRDM7 | Q9NQW5 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 12/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186191 | 0.64 | HRH4 (0.50) | PRDM9PRDM7MAPTGAANPC1 | |
| SCHEMBL28665714 | 0.62 | MAPT (0.64) | MAPTTHRBGAATP53LMNA | |
| SCHEMBL14996508 | 0.61 | PRDM9 (0.42) | PRDM9PRDM7GAAHSD17B10CYP1A2 | |
| SCHEMBL31546426 | 0.61 | MAPT (0.78) | MAPTTHRBGAATP53LMNA | |
| SCHEMBL13027974 | 0.61 | HRH4 (0.61) | MAPTGAAHTTNPC1KDM4E | |
| SCHEMBL28667773 | 0.61 | MAPT (0.62) | MAPTTHRBGAATP53LMNA | |
| SCHEMBL31546320 | 0.60 | MAPT (0.75) | MAPTTHRBGAATP53LMNA | |
| SCHEMBL13131094 | 0.59 | PRDM9 (0.40) | PRDM9PRDM7CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL425041 | 0.58 | HRH4 (0.56) | MAPTGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL30584791 | 0.58 | MAPT (0.63) | MAPTTP53LMNAHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122055154-A | Combination therapy | 澳大利亚悉尼大学 | 2026-05-15 | — | — | CN | claimed |
| WO-2025054665-A1 | COMBINATION THERAPY | THE UNIVERSITY OF SYDNEY (AU) | 2025-03-20 | — | — | WO | claimed |
| CN-122055154-A | Combination therapy | 澳大利亚悉尼大学 | 2026-05-15 | — | — | CN | disclosed |
| US-20250304585-A1 | SULFAMATE BASED COVALENT LIGAND-DIRECTED RELEASE (COLDR) COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2025-10-02 | — | — | US | disclosed |
| EP-4540249-A1 | SULFAMATE BASED COVALENT LIGAND-DIRECTED RELEASE (COLDR) COMPOUNDS | Yeda Research and Development Co. Ltd (IL) | 2025-04-23 | — | — | EP | disclosed |
| WO-2025054665-A1 | COMBINATION THERAPY | THE UNIVERSITY OF SYDNEY (AU) | 2025-03-20 | — | — | WO | disclosed |
| US-20240139326-A1 | METHACRYLAMIDES PROTEIN BINDERS AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2024-05-02 | — | — | US | disclosed |
| WO-2023242845-A1 | SULFAMATE BASED COVALENT LIGAND-DIRECTED RELEASE (CoLDR) COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240139326-A1 | METHACRYLAMIDES PROTEIN BINDERS AND USES THEREOF | STAMBP, HSPBP1, ECPAS | PRDM9 1983/4885PRDM7 3012/4885MAPT 911/4885 |
| US-20250304585-A1 | SULFAMATE BASED COVALENT LIGAND-DIRECTED RELEASE (COLDR) COMPOUNDS | CASR, NPSR1, GSR | PRDM9 3628/4885PRDM7 4296/4885MAPT 1375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.