Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.53 |
| ▸ | CTSL | P07711 | 6/20 | 0.53 |
| ▸ | CTSB | P07858 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863999 | 0.87 | CTSS (0.50) | CTSSCTSLCTSBCTSKATM | |
| SCHEMBL17357790 | 0.87 | CTSS (0.50) | CTSSCTSLCTSBCTSKATM | |
| SCHEMBL1199790 | 0.87 | ITGB3 (0.53) | CTSSCTSLCTSBCTSKATM | |
| SCHEMBL7513292 | 0.87 | ITGB3 (0.53) | CTSSCTSLCTSBCTSKATM | |
| SCHEMBL1199787 | 0.87 | ITGB3 (0.53) | CTSSCTSLCTSBCTSKATM | |
| SCHEMBL15936883 | 0.85 | KYNU (0.54) | CTSSCTSLCTSBCTSKATM | |
| SCHEMBL1199068 | 0.85 | KYNU (0.54) | CTSSCTSLCTSBCTSKATM | |
| SCHEMBL1199066 | 0.85 | KYNU (0.54) | CTSSCTSLCTSBCTSKATM | |
| SCHEMBL31276760 | 0.84 | CTSS (0.58) | CTSSCTSLCTSBCTSKMME | |
| SCHEMBL30801699 | 0.84 | CTSL (0.49) | CTSSCTSLCTSBCTSKATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786462-B1 | DC107 derivatives | KYOWA HAKKO KOGYO KK (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-5733924-A | BACTERICIDES AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0786462-A1 | DC107 DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |