Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.50 |
| ▸ | TGM2 | P21980 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483363 | 0.85 | ITGB3 (0.59) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL30101231 | 0.81 | P2RX7 (0.51) | TGM2 | |
| SCHEMBL9483544 | 0.80 | ITGB3 (0.59) | ITGB3ITGA2BOPRK1 | |
| SCHEMBL11257246 | 0.79 | TACR1 (0.63) | TGM2 | |
| SCHEMBL11257249 | 0.79 | TACR1 (0.63) | TGM2 | |
| SCHEMBL30054191 | 0.78 | CTSL (0.56) | TGM2 | |
| SCHEMBL11232416 | 0.77 | ITGB3 (0.62) | ITGB3ITGA2B | |
| SCHEMBL10997466 | 0.77 | CTSK (0.54) | TGM2CASP1 | |
| SCHEMBL9819756 | 0.76 | OPRK1 (0.65) | FAAHCHRM3SIGMAR1OPRK1 | |
| SCHEMBL8750811 | 0.75 | TACR1 (0.60) | ITGB3ITGA2BOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |