Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.57 |
| ▸ | RXRB | P28702 | 6/20 | 0.57 |
| ▸ | RXRG | P48443 | 2/20 | 0.57 |
| ▸ | DHODH | Q02127 | 4/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.46 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.46 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | USP5 | P45974 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2627825 | 0.86 | RXRA (0.68) | RXRARXRBRXRGEGLN1KIF11 | |
| SCHEMBL3087257 | 0.84 | RXRA (0.51) | RXRARXRBRXRGDHODH | |
| SCHEMBL2627836 | 0.84 | RXRA (0.71) | RXRARXRBRXRGAKR1C2 | |
| SCHEMBL15814719 | 0.83 | DHODH (0.69) | RXRARXRBRXRGDHODH | |
| SCHEMBL16488615 | 0.83 | DHODH (0.69) | RXRARXRBRXRGDHODH | |
| SCHEMBL18604547 | 0.81 | DHODH (0.67) | RXRARXRBRXRGDHODH | |
| SCHEMBL4246903 | 0.81 | DHODH (0.67) | RXRARXRBRXRGDHODH | |
| SCHEMBL14091422 | 0.80 | KIF11 (0.47) | RXRARXRBRXRGKIF11AKR1C2 | |
| SCHEMBL1356413 | 0.79 | FABP3 (0.56) | RXRARXRBRXRGCYP2C9CSNK2A2 | |
| SCHEMBL686581 | 0.79 | RXRA (0.65) | RXRARXRBRXRGDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7789943-B2 | Metal, ligand molecular sieves; temperature adjustable pores; controlling particle size | MIAMI UNIVERSITY (US) | 2010-09-07 | — | — | US | claimed |
| US-20080184881-A1 | MESH-ADJUSTABLE MOLECULAR SIEVE | MIAMI UNIVERSITY (US) | 2008-08-07 | — | — | US | claimed |
| US-20110064694-A1 | ANTI-HEPATITIS C ACTIVITY OF MESO-TETRAKIS-PORPHYRIN ANALOGUES | YALE UNIVERSITY (US) | 2011-03-17 | — | — | US | disclosed |
| US-7789943-B2 | Metal, ligand molecular sieves; temperature adjustable pores; controlling particle size | MIAMI UNIVERSITY (US) | 2010-09-07 | — | — | US | disclosed |
| US-20080184881-A1 | MESH-ADJUSTABLE MOLECULAR SIEVE | MIAMI UNIVERSITY (US) | 2008-08-07 | — | — | US | disclosed |
| US-20080184883-A1 | Mesh-Adjustable Molecular Sieve | MIAMI UNIVERSITY (US) | 2008-08-07 | — | — | US | disclosed |
| US-20080184883-A1 | Mesh-Adjustable Molecular Sieve | MIAMI UNIVERSITY (US) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080184881-A1 | MESH-ADJUSTABLE MOLECULAR SIEVE | TRPA1, TRPM4, TRPV4 | RXRA 3147/4885RXRB 3632/4885RXRG 3251/4885 |
| US-20110064694-A1 | ANTI-HEPATITIS C ACTIVITY OF MESO-TETRAKIS-PORPHYRIN ANALOGUES | HAVCR2, HCCS, HMBS | RXRA 1737/4885RXRB 1781/4885RXRG 1472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.