Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833130 | 0.87 | ALDH1A1 (0.47) | ALDH1A1LMNAGPR119CYP3A4CYP2D6 | |
| SCHEMBL30833127 | 0.87 | ALDH1A1 (0.47) | ALDH1A1LMNAGPR119CYP3A4CYP2D6 | |
| SCHEMBL30833107 | 0.84 | LMNA (0.43) | ALDH1A1LMNAGPR119CYP3A4CYP2D6 | |
| SCHEMBL25093578 | 0.83 | DDB1 (0.49) | GPR119KDM4EMAPTTHRBSMN1; SMN2 | |
| SCHEMBL30019254 | 0.83 | DDB1 (0.49) | GPR119KDM4EMAPTTHRBSMN1; SMN2 | |
| SCHEMBL30496855 | 0.82 | OPRK1 (0.43) | — | |
| SCHEMBL2421222 | 0.80 | GPR119 (0.53) | ALDH1A1LMNAGPR119KDM4EMAPT | |
| SCHEMBL24330056 | 0.79 | HSD11B1 (0.56) | GPR119KDM4EMAPTTHRBSMN1; SMN2 | |
| SCHEMBL12965677 | 0.78 | SMN1; SMN2 (0.52) | ALDH1A1LMNAGPR119CYP3A4CYP2D6 | |
| SCHEMBL23842631 | 0.78 | GPR119 (0.57) | GPR119KDM4EMAPTTHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587432-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | Cerevel Therapeutics, LLC (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059249-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | CEREVEL THERAPEUTICS, LLC (US) | 2024-03-21 | — | — | WO | disclosed |