Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833127 | 0.86 | ALDH1A1 (0.47) | LMNAALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30833130 | 0.86 | ALDH1A1 (0.47) | LMNAALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30833105 | 0.84 | ALDH1A1 (0.47) | LMNAALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29334889 | 0.77 | OPRK1 (0.45) | SMN1; SMN2MAPTGPR119 | |
| SCHEMBL31046541 | 0.77 | OPRK1 (0.45) | SMN1; SMN2MAPTGPR119 | |
| SCHEMBL12211044 | 0.75 | KDM4E (0.47) | LMNASMN1; SMN2MAPTKDM4ETHRB | |
| SCHEMBL24330056 | 0.74 | HSD11B1 (0.56) | SMN1; SMN2MAPTKDM4ETHRBGPR119 | |
| SCHEMBL23842631 | 0.73 | GPR119 (0.57) | SMN1; SMN2MAPTKDM4ETHRBGPR119 | |
| SCHEMBL12210723 | 0.73 | THRB (0.49) | SMN1; SMN2MAPTKDM4ETHRBGPR119 | |
| SCHEMBL1464028 | 0.72 | KDM4E (0.48) | SMN1; SMN2MAPTKDM4ETHRBGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587432-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | Cerevel Therapeutics, LLC (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059249-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | CEREVEL THERAPEUTICS, LLC (US) | 2024-03-21 | — | — | WO | disclosed |