SCHEMBL30833202 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	KCNH2	Q12809	13/20	0.45

▸	OPRK1	P41145	10/20	0.41

▸	ARG1	P05089	1/20	0.40

▸	ARG2	P78540	1/20	0.40

▸	LTA4H	P09960	1/20	0.39

▸	OPRM1	P35372	6/20	0.38

▸	OPRD1	P41143	4/20	0.38

▸	MEN1	O00255	1/20	0.37

▸	KMT2A	Q03164	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30833233	0.90	KCNH2 (0.56)	KCNH2OPRK1OPRM1OPRD1
SCHEMBL30833198	0.80	OPRK1 (0.47)	KCNH2OPRK1LTA4HOPRM1OPRD1
SCHEMBL30833213	0.70	OPRK1 (0.48)	KCNH2OPRK1LTA4HOPRM1OPRD1
SCHEMBL30833209	0.70	OPRK1 (0.56)	KCNH2OPRK1LTA4HOPRM1OPRD1
SCHEMBL30833216	0.70	KCNH2 (0.58)	KCNH2OPRK1OPRM1OPRD1
SCHEMBL30833227	0.68	OPRM1 (0.48)	KCNH2OPRK1LTA4HOPRM1OPRD1
SCHEMBL11098039	0.68	LTA4H (0.52)	ARG1ARG2LTA4HMEN1KMT2A
SCHEMBL3871503	0.67	LTA4H (0.52)	KCNH2OPRK1ARG1ARG2LTA4H
SCHEMBL3881484	0.67	DRD2 (0.48)	ARG1ARG2LTA4HMEN1KMT2A
SCHEMBL3881487	0.67	DRD2 (0.48)	ARG1ARG2LTA4HMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-117729914-A	Serotonin 5-HT2B inhibiting compounds	硕腾服务有限责任公司	2024-03-19	—	—	CN	disclosed