Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3 | P56703 | 2/20 | 0.35 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833508 | 0.88 | WNT3 (0.36) | WNT3SFRP1NR1H2NR1H3MEN1 | |
| SCHEMBL17949315 | 0.81 | STS (0.42) | HPGDGPR119NPSR1STS | |
| SCHEMBL30833488 | 0.80 | PDE8B (0.42) | NR1H2NR1H3PDE8BHCRTR2GPR119 | |
| SCHEMBL30833506 | 0.80 | SFRP1 (0.39) | WNT3SFRP1NR1H2NR1H3MEN1 | |
| SCHEMBL30833399 | 0.78 | MEN1 (0.38) | WNT3SFRP1NR1H2NR1H3MEN1 | |
| SCHEMBL30833421 | 0.77 | RORC (0.36) | WNT3SFRP1GAAHPGDLMNA | |
| SCHEMBL30833425 | 0.73 | RIPK1 (0.45) | WNT3SFRP1NR1H2NR1H3MEN1 | |
| SCHEMBL17942519 | 0.73 | HPGD (0.39) | GAAHPGDPDK1PDK2 | |
| SCHEMBL30833463 | 0.72 | MEN1 (0.43) | WNT3SFRP1NR1H2NR1H3MEN1 | |
| SCHEMBL30833504 | 0.72 | GPR119 (0.40) | WNT3SFRP1NR1H2NR1H3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |