Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 6/20 | 0.47 |
| ▸ | JAK3 | P52333 | 3/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | PAK4 | O96013 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | PRKACA | P17612 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.44 |
| ▸ | CLK2 | P49760 | 2/20 | 0.44 |
| ▸ | CDK9 | P50750 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.44 |
| ▸ | STK3 | Q13188 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.44 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190599 | 0.82 | ALK (0.49) | SYKJAK3DAPK3PRKD3MAP4K4 | |
| SCHEMBL30833700 | 0.80 | KDR (0.52) | SYKJAK3DAPK3PRKD3MAP4K4 | |
| SCHEMBL30833656 | 0.77 | ALK (0.48) | FLT3IGF1RALK | |
| SCHEMBL3388268 | 0.73 | SYK (0.52) | SYKSTK17APDPK1 | |
| SCHEMBL30833770 | 0.73 | IGF1R (0.42) | SYKJAK3DAPK3PRKD3MAP4K4 | |
| SCHEMBL3388259 | 0.73 | SYK (0.58) | SYKJAK3DAPK3PRKD3MAP4K4 | |
| SCHEMBL30833785 | 0.73 | ALK (0.51) | FLT3EGFRIGF1RMAPK9ALK | |
| SCHEMBL30833687 | 0.72 | ALK (0.50) | FLT3EGFRMETMAPK9ALK | |
| SCHEMBL30833797 | 0.72 | ALK (0.44) | JAK3FLT3EGFRIGF1RALK | |
| SCHEMBL30833709 | 0.70 | CDK1 (0.55) | SYKFLT3CLK2DYRK1ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |