Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 15/20 | 0.48 |
| ▸ | IGF1R | P08069 | 3/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833785 | 0.89 | ALK (0.51) | ALKIGF1RFLT3 | |
| SCHEMBL30833687 | 0.88 | ALK (0.50) | ALKFLT3 | |
| SCHEMBL30833666 | 0.85 | ALK (0.49) | ALKIGF1RFLT3 | |
| SCHEMBL29190714 | 0.84 | ALK (0.61) | ALKFLT3 | |
| SCHEMBL30833699 | 0.83 | EGFR (0.49) | ALKIGF1RAXL | |
| SCHEMBL30833661 | 0.83 | ALK (0.46) | ALKIGF1RFLT3AXL | |
| SCHEMBL30833669 | 0.81 | ALK (0.46) | ALKFLT3 | |
| SCHEMBL30833797 | 0.81 | ALK (0.44) | ALKIGF1RFLT3 | |
| SCHEMBL30833700 | 0.81 | KDR (0.52) | ALKIGF1RFLT3 | |
| SCHEMBL29190530 | 0.79 | ALK (0.61) | ALKFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |