Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 9/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833643 | 0.88 | ALK (0.43) | AURKAAURKBMAPK8TRPV1ALK | |
| SCHEMBL30833796 | 0.85 | IGF1R (0.46) | AURKAAURKBALDH1A1MAPK8TRPV1 | |
| SCHEMBL30833733 | 0.85 | PIN1 (0.36) | AURKAAURKBJAK2ALDH1A1TRPV1 | |
| SCHEMBL30833765 | 0.85 | PKMYT1 (0.38) | AURKAAURKBTRPV1ALKMAPT | |
| SCHEMBL30833703 | 0.85 | TRPV1 (0.47) | AURKBJAK2TRPV1CDC7CDK7 | |
| SCHEMBL30833745 | 0.78 | AURKA (0.43) | AURKAAURKBGLO1JAK2ALDH1A1 | |
| SCHEMBL10074538 | 0.77 | GLO1 (0.55) | AURKAAURKBGLO1JAK2ALDH1A1 | |
| SCHEMBL29904758 | 0.76 | ALK (0.41) | JAK2ALK | |
| SCHEMBL600580 | 0.76 | KMT2A (0.51) | AURKAAURKBGLO1JAK2ALDH1A1 | |
| SCHEMBL3864935 | 0.76 | AURKA (0.50) | AURKAAURKBGLO1JAK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |