Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 6/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584445 | 0.77 | MAPT (0.55) | MAPTALDH1A1RAB9ANPC1MEN1 | |
| Hydrochloric Acid SCHEMBL22609596 | 0.76 | MAPT (0.54) | MAPTALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL2718370 | 0.74 | SYK (0.53) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3718998 | 0.74 | MAPT (0.52) | MAPTALDH1A1RAB9ANPC1KCNH2 | |
| SCHEMBL28320641 | 0.73 | ALDH1A1 (0.50) | MAPTALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL28282980 | 0.72 | MAPK8 (0.52) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3638560 | 0.71 | MAPK1 (0.50) | MAPTALDH1A1RAB9ANPC1KCNH2 | |
| SCHEMBL28079567 | 0.70 | RPS6KB1 (0.65) | MAPTALDH1A1KCNH2HPGDKDM4E | |
| SCHEMBL30115228 | 0.69 | MAPT (0.47) | MAPTALDH1A1RAB9ANPC1KCNH2 | |
| SCHEMBL3716905 | 0.69 | ALDH1A1 (0.62) | MAPTALDH1A1RAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149409-B | (hetero) aryl amide compound with protein kinase inhibition activity | 中国药科大学 | 2024-03-22 | — | — | CN | disclosed |