SCHEMBL3084259

SCHEMBL3084259

CC(C)C[C@H](N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N1CCC[C@H]1[C]=O)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CALCRL Q16602 4/20 0.41
▸ DPP4 P27487 7/20 0.41
▸ CASP3 P42574 4/20 0.41
▸ CASP2 P42575 4/20 0.41
▸ DPP8 Q6V1X1 4/20 0.39
▸ DPP9 Q86TI2 1/20 0.39
▸ DPP7 Q9UHL4 1/20 0.39
▸ CTSD P07339 2/20 0.38
▸ BACE1 P56817 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3083059 0.90 DPP4 (0.47) DPP4DPP8DPP9DPP7
SCHEMBL16468657 0.86 ACE (0.50) CALCRLCASP3CASP2
SCHEMBL2185084 0.84 CALCRL (0.48) CALCRLCASP3CASP2
SCHEMBL30525434 0.81 CALCRL (0.50) CALCRL
SCHEMBL30525445 0.78 CAPN1 (0.53) CALCRL
SCHEMBL30401176 0.77 SLC6A2 (0.49) CALCRL
SCHEMBL30051863 0.77 ACE (0.49) DPP4DPP8DPP9DPP7
SCHEMBL7406032 0.76 DPP4 (0.62) DPP4DPP8DPP9DPP7
SCHEMBL7029434 0.76 DPP4 (0.62) DPP4DPP8DPP9DPP7
SCHEMBL29521253 0.76 CALCRL (0.49) CALCRL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054519-A1 DERIVATIVES OF MONOSACCHARIDES AS 5-LIPOXYGENASE INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2009-02-26 — — US claimed
EP-1915160-A2 DERIVATIVES OF MONOSACCHARIDES FOR THE TREATMENT OF COPD AND ALLERGIC RHINITIS Ranbaxy Laboratories Limited (IN) 2008-04-30 — — EP claimed
WO-2007010499-A2 DERIVATIVES OF MONOSACCHARIDES FOR THE TREATMENT OF COPD AND ALLERGIC RHINITIS RANBAXY LABORATORIES LIMITED (IN) 2007-01-25 — — WO claimed
CN-1254478-C Derivatives of monosaccharides as well adhesion inhibitors RANBAXY LAB LTD (IN) 2006-05-03 — — CN claimed
WO-2004071515-A1 PREPARATION OF MONOSACCHARIDE DERIVATIVES RANBAXY LABORATORIES LIMITED (IN) 2004-08-26 — — WO claimed
EP-1144425-B1 DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS RANBAXY LAB LTD (IN) 2004-06-16 — — EP claimed
CN-1343212-A Derivatives of monosaccharides as well adhesion inhibitors RANBAXY LAB LTD (IN) 2002-04-03 — — CN claimed
US-6329344-B1 UREA DERIVATIVE OF ALKYLENE DIOXYFURAN ETHERS RANBAXY LABORATORIES LIMITED (IN) 2001-12-11 — — US claimed
EP-1144425-A1 DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES, LTD. (IN) 2001-10-17 — — EP claimed
WO-2000042053-A1 DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES LIMITED (US) 2000-07-20 — — WO claimed
US-7790689-B2 Monosaccharide derivatives RANBAXY LABORATORIES LIMITED (IN) 2010-09-07 — — US disclosed
US-20090054519-A1 DERIVATIVES OF MONOSACCHARIDES AS 5-LIPOXYGENASE INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2009-02-26 — — US disclosed
US-20090048186-A1 Monosaccharide Derivatives as Anti-Inflammatory and/or Anti-Cancer Agents RANBAXY LABORATORIES LIMITED (IN) 2009-02-19 — — US disclosed
US-20080300196-A1 MONOSACCHARIDE DERIVATIVES RANBAXY LABORATORIES LIMITED (IN) 2008-12-04 — — US disclosed
EP-1953170-A1 Monosaccharide derivatives as anti-inflammatory agents Ranbaxy Laboratories Limited (IN) 2008-08-06 — — EP disclosed
EP-1144425-B1 DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS RANBAXY LAB LTD (IN) 2004-06-16 — — EP disclosed
CN-1343212-A Derivatives of monosaccharides as well adhesion inhibitors RANBAXY LAB LTD (IN) 2002-04-03 — — CN disclosed
US-6329344-B1 UREA DERIVATIVE OF ALKYLENE DIOXYFURAN ETHERS RANBAXY LABORATORIES LIMITED (IN) 2001-12-11 — — US disclosed
EP-1144425-A1 DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES, LTD. (IN) 2001-10-17 — — EP disclosed
WO-2000042053-A1 DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES LIMITED (US) 2000-07-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080300196-A1 MONOSACCHARIDE DERIVATIVES HLA-DRB1, ASGR1, CSGALNACT1 CALCRL 1491/4885DPP4 393/4885CASP3 1412/4885
US-20090048186-A1 Monosaccharide Derivatives as Anti-Inflammatory and/or Anti-Cancer Agents HLA-DRB1, MUC1, ASGR1 CALCRL 1433/4885DPP4 330/4885CASP3 1494/4885
US-20090054519-A1 DERIVATIVES OF MONOSACCHARIDES AS 5-LIPOXYGENASE INHIBITORS ALOX5, ALOX15, ALOX15B CALCRL 4577/4885DPP4 973/4885CASP3 2686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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