SCHEMBL308455

SCHEMBL308455

CCCCN(C(C)=O)C1CC(C)(C)N(O)C(C)(C)C1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 1/20 0.38
ALDH1A1 P00352 2/20 0.37
ALOX15 P16050 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.35
THRB P10828 1/20 0.34
LMNA P02545 1/20 0.33
PTBP1 P26599 1/20 0.33
UBE2M P61081 1/20 0.31
DCUN1D1 Q96GG9 1/20 0.31
GAA P10253 2/20 0.31
PKM P14618 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4960134 0.88 ALDH1A1 (0.37) SRD5A1ALDH1A1ALOX15L3MBTL1LMNA
SCHEMBL272291 0.82 KDM4C (0.37) SRD5A1ALDH1A1ALOX15
SCHEMBL272810 0.82 KDM4C (0.37) SRD5A1ALDH1A1ALOX15
SCHEMBL8459911 0.82 SRD5A1 (0.38) SRD5A1ALDH1A1L3MBTL1THRBLMNA
SCHEMBL4417247 0.79 L3MBTL1 (0.35) SRD5A1ALDH1A1ALOX15L3MBTL1THRB
SCHEMBL11140293 0.79 SRD5A1 (0.34) SRD5A1L3MBTL1THRBUBE2MDCUN1D1
SCHEMBL14224276 0.78 SRD5A1 (0.34) SRD5A1THRB
SCHEMBL1138443 0.78 SRD5A1 (0.34) SRD5A1THRB
SCHEMBL9400312 0.77 TSHR (0.37) SRD5A1ALDH1A1THRBGAA
SCHEMBL1138617 0.77 L3MBTL1 (0.34) SRD5A1ALDH1A1L3MBTL1THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095006-A1 DERIVATIVES OF 1-OXYL-4-HYDROXY-OR 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE AS POLYMERIZATION INHIBITORS FOR (METH) ACRYLATE MONOMERS Ciba SC Holding AG (CH) 2001-05-02 EP claimed
WO-2000003965-A1 DERIVATIVES OF 1-OXYL-4-HYDROXY- OR 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE AS POLYMERIZATION INHIBITORS FOR (METH)ACRYLATE MONOMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-01-27 WO claimed
US-5928558-A STORAGE STABILITY CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-07-27 US claimed
US-8134009-B2 Process for the oxidation of secondary amines into the corresponding nitroxides BASF SE (DE) 2012-03-13 US disclosed
US-20100305322-A1 Process for the Oxidation of Secondary Amines into the Corresponding Nitroxides CIBA SPECIALTY CHEMICALS CORPORATION 2010-12-02 US disclosed
EP-2030963-A2 Derivatives of 1-oxyl-4-hydroxy-or 4-amino-2,2,6,6-tetramethylpiperidine as polymerization inhibitors for (meth) acrylate monomers Ciba Holding Inc. (CH) 2009-03-04 EP disclosed
EP-1095006-A1 DERIVATIVES OF 1-OXYL-4-HYDROXY-OR 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE AS POLYMERIZATION INHIBITORS FOR (METH) ACRYLATE MONOMERS Ciba SC Holding AG (CH) 2001-05-02 EP disclosed
EP-1000032-A1 INHIBITION OF PULP AND PAPER YELLOWING USING NITROXIDES AND OTHER COADDITIVES Ciba SC Holding AG (CH) 2000-05-17 EP disclosed
WO-2000003965-A1 DERIVATIVES OF 1-OXYL-4-HYDROXY- OR 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE AS POLYMERIZATION INHIBITORS FOR (METH)ACRYLATE MONOMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-01-27 WO disclosed
US-5928558-A STORAGE STABILITY CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-07-27 US disclosed
WO-1999005108-A1 INHIBITION OF PULP AND PAPER YELLOWING USING NITROXIDES AND OTHER COADDITIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305322-A1 Process for the Oxidation of Secondary Amines into the Corresponding Nitroxides NOS2, NOS1, NOS3 SRD5A1 1821/4885ALDH1A1 1179/4885ALOX15 797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.