Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30853380 | 0.90 | ATR (0.30) | — | |
| SCHEMBL29844186 | 0.79 | SERPINE1 (0.36) | DHODH | |
| SCHEMBL30853376 | 0.65 | TLR8 (0.41) | ALDH1A1HPGDLMNADHODH | |
| SCHEMBL29168454 | 0.64 | PKM (0.31) | — | |
| SCHEMBL30853389 | 0.56 | DGAT1 (0.33) | — | |
| SCHEMBL2428009 | 0.55 | TLR8 (0.38) | DHODH | |
| SCHEMBL20239607 | 0.54 | ALDH1A1 (0.40) | ALDH1A1HPGDLMNA | |
| SCHEMBL25207713 | 0.53 | HSD17B10 (0.42) | DHODH | |
| SCHEMBL21723279 | 0.48 | KDM4E (0.47) | ALDH1A1HPGDLMNA | |
| SCHEMBL12155222 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |