Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30853366 | 0.90 | ALDH1A1 (0.30) | — | |
| SCHEMBL29844186 | 0.69 | SERPINE1 (0.36) | — | |
| SCHEMBL30853389 | 0.67 | DGAT1 (0.33) | — | |
| SCHEMBL30853360 | 0.66 | TLR8 (0.41) | — | |
| SCHEMBL29168359 | 0.65 | AXL (0.31) | KDM4E | |
| SCHEMBL29163102 | 0.61 | NPC1 (0.37) | KDM4E | |
| SCHEMBL30437637 | 0.61 | NPC1 (0.37) | KDM4E | |
| SCHEMBL30438125 | 0.59 | MEN1 (0.32) | KDM4E | |
| SCHEMBL29154699 | 0.58 | SMN1; SMN2 (0.34) | KDM4E | |
| SCHEMBL26664268 | 0.57 | L3MBTL1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |