Sugi Predict

Sugi Predict / Compounds / SCHEMBL308577

SCHEMBL308577

SCHEMBL308577

CCc1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.56
▸ MEN1 O00255 1/20 0.56
▸ ALDH1A1 P00352 6/20 0.54
▸ HPGD P15428 5/20 0.54
▸ HSD17B10 Q99714 4/20 0.54
▸ CYP3A4 P08684 2/20 0.54
▸ TSHR P16473 2/20 0.54
▸ TDP1 Q9NUW8 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.54
▸ KDM4E B2RXH2 4/20 0.49
▸ CYP1A2 P05177 4/20 0.48
▸ CYP1B1 Q16678 2/20 0.48
▸ CYP1A1 P04798 1/20 0.48
▸ MAPT P10636 1/20 0.46
▸ ERBB2 P04626 1/20 0.45
▸ FYN P06241 1/20 0.45
▸ MAOA P21397 1/20 0.45
▸ ACHE P22303 1/20 0.45
▸ AHR P35869 1/20 0.45
▸ THRB P10828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29156709 0.98 KMT2A (0.54) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL11338015 0.91 ALDH1A1 (0.71) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL28943977 0.86 ALDH1A1 (0.45) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL1618749 0.85 ALDH1A1 (0.43) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL27705873 0.83 CYP1A2 (0.52) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL397619 0.83 KMT2A (0.57) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL2928914 0.83 KMT2A (0.56) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL1191102 0.82 KMT2A (0.49) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL25334951 0.82 KMT2A (0.55) KMT2AMEN1ALDH1A1HPGDHSD17B10
Ethyne SCHEMBL27799323 0.82 ALDH1A1 (0.40) KMT2AMEN1ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10281831-B2 Imaging members comprising capped structured organic film compositions XEROX CORPORATION (US) 2019-05-07 — — US claimed
US-20160259256-A1 IMAGING MEMBERS COMPRISING CAPPED STRUCTURED ORGANIC FILM COMPOSITIONS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2016-09-08 — — US claimed
EP-1081164-B1 Binder resin with reduced hydroxyl content XEROX CORP (US) 2015-04-01 — — EP claimed
US-8097387-B2 Photoreceptors comprising aligned nano-sized domains of charge transport components that have significant intermolecular pi-pi orbital overlap XEROX CORPORATION (US) 2012-01-17 — — US claimed
US-20090226829-A1 PHOTORECEPTORS COMPRISING ALIGNED NANO-SIZED DOMAINS OF CHARGE TRANSPORT COMPONENTS THAT HAVE SIGNIFICANT INTERMOLECULAR PI-PI ORBITAL OVERLAP XEROX CORPORATION (US) 2009-09-10 — — US claimed
US-4282298-A OVERCOATING THE PHOTOCONDUCTIVE LAYER WITH A CHARGE TRANSFER COMPOUND OF AROMATIC POLYNUCLEAR STRUCTURE; XEROGRAPHY XEROX CORPORATION (US) 1981-08-04 — — US claimed
US-3956524-A Method for the preparation of electrostatographic photoreceptors XEROX CORPORATION (US) 1976-05-11 — — US claimed
US-3933772-A ALKYLPYRENE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-01-20 — — US claimed
WO-2024016071-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2024-01-25 — — WO disclosed
US-11067889-B2 Compound, composition, and method for producing same, underlayer film forming material for lithography, composition for underlayer film formation for lithography, and purification method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-07-20 — — US disclosed
CN-107850848-B Compound and method for producing same 三菱瓦斯化学株式会社 2021-06-04 — — CN disclosed
US-10723690-B2 (Meth)acryloyl compound and method for producing same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-07-28 — — US disclosed
US-10649353-B2 Tethered metal dioxide for imaging members XEROX CORPORATION (US) 2020-05-12 — — US disclosed
US-20200110344-A1 TETHERED METAL DIOXIDE FOR IMAGING MEMBERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2020-04-09 — — US disclosed
US-4025188-A Photoactive device for xerography XEROX CORPORATION (US) 1977-05-24 — — US disclosed
US-4016135-A STABILIZATION OF A POLYMERIC RESIN WITH AN ALKYL SUBSTITUTED TETRACYCLIC COMPOUND KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1977-04-05 — — US disclosed
US-3966674-A PROPYLFLUORANTHENE, PROPYLPYRENE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-06-29 — — US disclosed
US-3956524-A Method for the preparation of electrostatographic photoreceptors XEROX CORPORATION (US) 1976-05-11 — — US disclosed
US-3953207-A Composite layered photoreceptor XEROX CORPORATION (US) 1976-04-27 — — US disclosed
US-3933772-A ALKYLPYRENE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-01-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11067889-B2 Compound, composition, and method for producing same, underlayer film forming material for lithography, composition for underlayer film formation for lithography, and purification method C5, C9, PRMT9 KMT2A 391/4885MEN1 146/4885ALDH1A1 3122/4885
US-10723690-B2 (Meth)acryloyl compound and method for producing same MTR, MRM1, MT-CO1 KMT2A 10/4885MEN1 858/4885ALDH1A1 153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.