Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31678785 | 0.83 | PTGS1 (0.53) | ALDH1A1PTGS1PTGS2KMT2AL3MBTL1 | |
| SCHEMBL29757486 | 0.80 | KMT2A (0.47) | ALDH1A1PTGS1PTGS2KMT2AMEN1 | |
| SCHEMBL31678874 | 0.72 | PTGS1 (0.47) | ALDH1A1PTGS1PTGS2CYP2C9NAMPT | |
| SCHEMBL14241688 | 0.69 | ALDH1A1 (0.53) | ALDH1A1KMT2AL3MBTL1MEN1HPGD | |
| SCHEMBL30610165 | 0.67 | APLNR (0.46) | PTGS1PTGS2OPRM1HDAC4 | |
| SCHEMBL27953545 | 0.66 | CA1 (0.60) | ALDH1A1CTSD | |
| SCHEMBL27673209 | 0.66 | ALDH1A1 (0.50) | ALDH1A1KMT2AL3MBTL1MEN1HPGD | |
| SCHEMBL1423573 | 0.66 | KEAP1 (0.60) | ALDH1A1PTGS1PTGS2KMT2AL3MBTL1 | |
| SCHEMBL30282963 | 0.64 | ROCK2 (0.56) | ALDH1A1KMT2AL3MBTL1NAMPTMEN1 | |
| SCHEMBL2447209 | 0.64 | HDAC4 (0.47) | ALDH1A1PTGS1PTGS2KMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728168-B | Triazole carbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |