Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.53 |
| ▸ | CTSS | P25774 | 9/20 | 0.53 |
| ▸ | CTSL | P07711 | 9/20 | 0.53 |
| ▸ | CTSB | P07858 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15966110 | 0.91 | CTSK (0.51) | CTSKCTSSCTSLCTSB | |
| SCHEMBL16474289 | 0.87 | PRMT5 (0.47) | CTSL | |
| SCHEMBL30511036 | 0.86 | KDM1A (0.53) | CTSL | |
| SCHEMBL20528094 | 0.86 | KDM1A (0.53) | CTSL | |
| SCHEMBL20522962 | 0.86 | KDM1A (0.53) | CTSL | |
| SCHEMBL4738328 | 0.83 | OPRD1 (0.53) | — | |
| SCHEMBL337363 | 0.83 | OPRD1 (0.53) | — | |
| SCHEMBL336766 | 0.83 | OPRD1 (0.53) | — | |
| SCHEMBL4188272 | 0.83 | CTSK (0.57) | CTSKCTSSCTSLCTSB | |
| SCHEMBL28456201 | 0.81 | ATM (0.49) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100227856-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-09-09 | — | — | US | disclosed |
| US-20100227856-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-09-09 | — | — | US | disclosed |
| US-20100227856-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227856-A1 | NOVEL COMPOUNDS | TRPV4, TRPV1, TRPA1 | CTSK 3178/4885CTSS 2197/4885CTSL 3889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.