Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22554383 | 1.00 | CA2 (0.54) | CA2TSHRALDH1A1POLBMAPT | |
| SCHEMBL21156703 | 0.87 | CYP19A1 (0.49) | CA2ALDH1A1POLBKDM4ECYP3A4 | |
| SCHEMBL30866423 | 0.87 | CYP19A1 (0.49) | CA2ALDH1A1POLBKDM4ECYP3A4 | |
| SCHEMBL22554349 | 0.80 | ALDH1A1 (0.54) | TSHRALDH1A1POLBMAPTRAB9A | |
| SCHEMBL21157861 | 0.78 | GPR55 (0.48) | POLBRAB9ASMN1; SMN2 | |
| SCHEMBL30866420 | 0.75 | PTPN1 (0.54) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL21122490 | 0.75 | PTPN1 (0.54) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL8279278 | 0.75 | LMNA (0.60) | CA2TSHRALDH1A1POLBMAPT | |
| SCHEMBL2095593 | 0.73 | CA2 (1.00) | CA2TSHRALDH1A1POLBRAB9A | |
| SCHEMBL22554348 | 0.73 | RAB9A (0.46) | TSHRALDH1A1POLBRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587239-B | Method for producing lactam compound and lactam compound produced by the method | 基础科学研究院 | 2024-04-02 | — | — | CN | disclosed |