Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987418 | 0.80 | CYP1A2 (0.58) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL2547243 | 0.80 | CYP1A2 (0.65) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL6961047 | 0.78 | CYP1A2 (0.56) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL8818467 | 0.78 | CYP1A2 (0.56) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL3086830 | 0.78 | CYP1A2 (0.56) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL8984631 | 0.76 | CYP1A2 (0.54) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL4556174 | 0.76 | MAPT (0.56) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL2843838 | 0.75 | KCNN4 (0.52) | CYP1A2MAPTKMT2AKCNN4CYP2C9 | |
| SCHEMBL2981609 | 0.74 | CES1 (0.52) | CYP1A2TSHRMAPTKMT2ACYP2C19 | |
| SCHEMBL6037489 | 0.73 | CYP2C9 (0.56) | CYP1A2MAPTKMT2AKCNN4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801706-A | ANTIARRHYTHMIA HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-01-31 | — | — | US | claimed |
| EP-1319642-B1 | Method of Preparing a Halogenated Compound | OTSUKA KAGAKU KK (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-1132391-B1 | PROCESS FOR THE PREPARATION OF 3-SULFONYLOXY-3-CEPHEM COMPOUNDS | OTSUKA KAGAKU KK (JP) | 2006-11-15 | — | — | EP | disclosed |
| EP-1447406-B1 | 3-Cephem derivative crystal | OTSUKA KAGAKU KK (JP) | 2006-08-09 | — | — | EP | disclosed |
| US-6887992-B2 | 3-cephem derivative crystal | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |
| EP-1447406-A1 | 3-Cephem derivative crystal | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-0976700-B1 | PROCESS FOR HALOGENATING HYDROXYL GROUP | OTSUKA KAGAKU KK (JP) | 2004-07-28 | — | — | EP | disclosed |
| EP-1061082-B1 | PROCESS FOR THE PREPARATION OF BETA-HYDROXY ESTERS | OTSUKA KAGAKU KK (JP) | 2004-07-14 | — | — | EP | disclosed |
| EP-1227100-B1 | 3-CEPHEM DERIVATIVE CRYSTAL AND METHOD FOR PREPARING THE SAME | OTSUKA KAGAKU KK (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-20040073023-A1 | 3-cephem derivative crystal | MORIYOSHI TAKASHI (JP) | 2004-04-15 | — | — | US | disclosed |
| US-5196530-A | Cyclization with reducing metal | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1993-03-23 | — | — | US | disclosed |
| EP-0529081-A1 | HALOGENATED $g(b)-LACTAM COMPOUND AND PRODUCTION OF 3-HYDROXYCEPHEM DERIVATIVE THEREFROM | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1993-03-03 | — | — | EP | disclosed |
| EP-0507124-A2 | Process for preparing cephem derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1992-10-07 | — | — | EP | disclosed |
| EP-0503604-A2 | Allenyl beta-lactam compounds and process for preparing same | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0503603-A2 | Process for preparing 2-exo-methylenepenam derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0503597-A2 | Penam derivatives and processes for producing the same | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-5142040-A | Oxidizing inpresence of oxygen with 3-halomethylcephem derivative | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| EP-0445821-A1 | Process for preparing a 3-formylcephem derivative | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4801706-A | ANTIARRHYTHMIA HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |
| US-4801706-A | ANTIARRHYTHMIA HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040073023-A1 | 3-cephem derivative crystal | CRYAA, CRYAB, PCCA | CYP1A2 939/4885TSHR 4751/4885MAPT 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.