SCHEMBL30869488

SCHEMBL30869488

c1cc2cc(-c3ccc4c(c3)N(CCN3CCOCC3)c3cc(-c5ccc6[nH]cnc6c5)ccc3O4)ccc2[nH]1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.40
FLT1 P17948 1/20 0.40
JAK2 O60674 1/20 0.38
PRKDC P78527 1/20 0.38
MTOR P42345 3/20 0.37
PIK3CA P42336 2/20 0.37
CD274 Q9NZQ7 1/20 0.37
CYP2C9 P11712 1/20 0.37
ATR Q13535 1/20 0.37
GRIA1 P42261 1/20 0.37
FLT3 P36888 1/20 0.36
PIK3CG P48736 1/20 0.36
PRKCQ Q04759 2/20 0.36
PRKCD Q05655 1/20 0.36
MAP4K4 O95819 1/20 0.35
ERBB2 P04626 1/20 0.35
MAPK9 P45984 1/20 0.35
CSNK1D P48730 1/20 0.35
PRKD2 Q9BZL6 1/20 0.35
SLK Q9H2G2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869459 0.84 PIM1 (0.45) EGFRFLT1JAK2PRKDCMTOR
SCHEMBL30869770 0.80 PRKDC (0.37) EGFRFLT1JAK2PRKDCMTOR
SCHEMBL30869782 0.80 CHRNA7 (0.38) EGFRFLT1JAK2PRKDCMTOR
SCHEMBL30869719 0.79 KDM1A (0.42) EGFRFLT1JAK2PRKDCMTOR
SCHEMBL30869693 0.79 WDR5 (0.36) EGFRFLT1JAK2PRKDCMTOR
SCHEMBL30869460 0.77 WDR5 (0.42) PRKDCMTORPIK3CACD274CYP2C9
SCHEMBL30869715 0.77 PRKDC (0.40) EGFRFLT1JAK2PRKDCMTOR
SCHEMBL30869742 0.75 CTSS (0.39) EGFRFLT1MTORPIK3CAALDH1A1
SCHEMBL30869625 0.74 WDR5 (0.42) PIK3CACD274KDM4EALDH1A1MAPT
SCHEMBL30869480 0.73 PRKDC (0.37) FLT1JAK2PRKDCMTORPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed