SCHEMBL30869697

SCHEMBL30869697

CN1C[C@H]2C[C@@H]1CN2CCN1c2ccc(-c3cccc4[nH]ncc34)cc2Sc2cc(-c3cccc4[nH]ncc34)ccc21

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BRAF P15056 14/20 0.42
CHRNA7 P36544 4/20 0.40
KCNH2 Q12809 3/20 0.40
ABL1 P00519 1/20 0.39
EGFR P00533 1/20 0.39
RAF1 P04049 1/20 0.39
LCK P06239 1/20 0.39
YES1 P07947 1/20 0.39
RET P07949 1/20 0.39
EPHA1 P21709 1/20 0.39
TEK Q02763 1/20 0.39
MAPK14 Q16539 1/20 0.39
METAP2 P50579 1/20 0.37
BRD4 O60885 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869706 0.89 CHRNA7 (0.38) BRAFCHRNA7KCNH2ABL1EGFR
SCHEMBL30869548 0.88 BRAF (0.42) BRAFCHRNA7KCNH2ABL1EGFR
SCHEMBL30869669 0.85 ABL1 (0.36) BRAFABL1RET
SCHEMBL30869668 0.85 NUDT1 (0.39) CHRNA7KCNH2MAPK14BRD4
SCHEMBL30869756 0.78 PIK3CG (0.49) METAP2
SCHEMBL30869658 0.78 CHRNA7 (0.47) CHRNA7KCNH2ABL1
SCHEMBL30869727 0.77 BRAF (0.39) BRAFABL1
SCHEMBL30869815 0.74 BRAF (0.45) BRAFABL1METAP2BRD4
SCHEMBL30869774 0.74 PARP1 (0.38) BRAFABL1RET
SCHEMBL30869495 0.73 NUDT1 (0.39) BRAFMAPK14BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 BRAF 4257/4885CHRNA7 1850/4885KCNH2 851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.