SCHEMBL30869663

SCHEMBL30869663

c1cc(-c2ccc3c(c2)Sc2cc(-c4ccnc5c4cnn5C4CCCCO4)ccc2N3CCN2CCOCC2)c2cnn(C3CCCCO3)c2n1

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 1/20 0.39
ATR Q13535 16/20 0.38
KDM1A O60341 2/20 0.38
ACVR1 Q04771 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869528 0.89 CD274 (0.39) CD274ATRACVR1
SCHEMBL30869421 0.84 ATR (0.33) ATR
SCHEMBL30869686 0.80 ATR (0.34) CD274ATR
SCHEMBL30869525 0.78 ATR (0.35) ATR
SCHEMBL30869650 0.75 PIK3CD (0.47) KDM1A
SCHEMBL30869532 0.73 ATR (0.38) ATR
SCHEMBL32682876 0.71 KDM1A (0.39) ATRKDM1A
SCHEMBL30869711 0.70 PRKCQ (0.45) KDM1A
SCHEMBL30897220 0.67 CYP4F2 (0.43) ATR
SCHEMBL30869756 0.67 PIK3CG (0.49) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 CD274 4699/4885ATR 4022/4885KDM1A 3264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.