SCHEMBL30869711

SCHEMBL30869711

c1cc(-c2ccc3c(c2)Sc2cc(-c4ccnc5[nH]ncc45)ccc2N3CCN2CCOCC2)c2cn[nH]c2c1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRKCQ Q04759 3/20 0.45
PIK3CG P48736 2/20 0.43
PIK3CA P42336 12/20 0.41
PIK3CD O00329 2/20 0.41
PIK3CB P42338 1/20 0.41
KDM1A O60341 1/20 0.41
TLR8 Q9NR97 2/20 0.41
TLR7 Q9NYK1 2/20 0.41
NUDT1 P36639 1/20 0.41
MTOR P42345 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869650 0.93 PIK3CD (0.47) PRKCQPIK3CAPIK3CDPIK3CBKDM1A
SCHEMBL30869756 0.92 PIK3CG (0.49) PIK3CGPIK3CAPIK3CDPIK3CBKDM1A
SCHEMBL30869877 0.83 PIK3CD (0.48) PRKCQPIK3CAPIK3CDPIK3CBTLR8
SCHEMBL30869587 0.83 PIK3CG (0.41) PIK3CGPIK3CAPIK3CDPIK3CBKDM1A
SCHEMBL30869713 0.82 PIK3CA (0.36) PIK3CGPIK3CAPIK3CDKDM1A
SCHEMBL30869729 0.78 PIK3CG (0.48) PIK3CGPIK3CAPIK3CDPIK3CBMTOR
SCHEMBL32682887 0.77 EGFR (0.52) PRKCQPIK3CAKDM1A
SCHEMBL30869758 0.75 KDM1A (0.47) PIK3CAKDM1A
SCHEMBL30869495 0.73 NUDT1 (0.39) PRKCQTLR8TLR7NUDT1
SCHEMBL30869668 0.73 NUDT1 (0.39) PRKCQTLR8TLR7NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 PRKCQ 96/4885PIK3CG 159/4885PIK3CA 475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.