Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.33 |
| ▸ | FPR2 | P25090 | 4/20 | 0.33 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096008 | 0.87 | METAP2 (0.35) | METAP2FPR2METAP1ALDH1A1CYP3A4 | |
| SCHEMBL3101487 | 0.87 | ALDH1A1 (0.40) | FPR2ALDH1A1CA12CA1CA2 | |
| SCHEMBL3098722 | 0.83 | FPR2 (0.43) | FPR2TDP1PPARDTSHRCA12 | |
| SCHEMBL3090739 | 0.82 | NOS2 (0.37) | — | |
| SCHEMBL3090743 | 0.82 | NOS2 (0.37) | — | |
| SCHEMBL3091741 | 0.82 | PPARD (0.43) | FPR2ALDH1A1PPARDTSHRCA12 | |
| SCHEMBL2989543 | 0.82 | ECE1 (0.36) | METAP2METAP1MEN1KMT2ATSHR | |
| SCHEMBL2989547 | 0.82 | ECE1 (0.36) | METAP2METAP1MEN1KMT2ATSHR | |
| SCHEMBL3097954 | 0.81 | GGH (0.49) | — | |
| SCHEMBL3109219 | 0.81 | FPR2 (0.34) | FPR2PPARDTSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |