SCHEMBL4616262

SCHEMBL4616262

Cc1ccc(S(=O)(=O)c2ccc(C)cc2-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.43
PTGS2 P35354 2/20 0.42
ALKBH3 Q96Q83 1/20 0.41
GRM2 Q14416 1/20 0.40
APP P05067 1/20 0.39
PTGS1 P23219 1/20 0.39
BCHE P06276 1/20 0.38
ACHE P22303 1/20 0.38
GRM5 P41594 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
FLT1 P17948 1/20 0.37
FLT4 P35916 1/20 0.37
KDR P35968 1/20 0.37
KIF11 P52732 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4848783 0.89 AGTR1 (0.43) AGTR1PTGS2ALKBH3GRM2APP
SCHEMBL10977080 0.85 S100A4 (0.45) PTGS2PTGS1ALDH1A1CYP3A4MAPK1
SCHEMBL31453311 0.82 ALDH1A1 (0.41) PTGS2ALKBH3PTGS1ACHEALDH1A1
SCHEMBL3164778 0.82 MAOB (0.45) ACHEALDH1A1MAPK1MAOAMAOB
SCHEMBL4126510 0.81 HDAC7 (0.47) PTGS2ALDH1A1MAOAMAOB
SCHEMBL28530317 0.79 ALKBH3 (0.52) PTGS2ALKBH3GRM2PTGS1ACHE
SCHEMBL3316491 0.79 ALKBH3 (0.42) PTGS2ALKBH3PTGS1ALDH1A1
SCHEMBL30874282 0.79 MCL1 (0.39) AGTR1PTGS2GRM2APPALDH1A1
SCHEMBL9468835 0.79 POLB (0.51) PTGS2PTGS1CYP3A4MAPK1MEN1
SCHEMBL3446544 0.79 GRM5 (0.44) PTGS2PTGS1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107561863-B Positive photosensitive resin composition and application thereof 奇美实业股份有限公司 2022-09-16 CN disclosed
CN-106909028-B Photosensitive resin composition, protective film and liquid crystal display element 奇美实业股份有限公司 2020-06-05 CN disclosed
CN-104950580-B Photosensitive polysiloxane composition and application thereof 奇美实业股份有限公司 2020-01-03 CN disclosed
US-10162260-B2 Photosensitive resin composition, protective film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-12-25 US disclosed
US-20170168390-A1 PHOTOSENSITIVE RESIN COMPOSITION, PROTECTIVE FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-06-15 US disclosed
EP-1879859-A2 DIARYLSULFONE SULFONAMIDES AND USE THEROF Wyeth a Corporation of the State of Delaware (US) 2008-01-23 EP disclosed
US-20060276464-A1 Diarylsulfone sulfonamides and use thereof WYETH (US) 2006-12-07 US disclosed
WO-2006124875-A2 DIARYLSULFONE SULFONAMIDES AND USE THEROF WYETH (US) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060276464-A1 Diarylsulfone sulfonamides and use thereof SFRP1, SOS1, FZD7 AGTR1 3547/4885PTGS2 3457/4885ALKBH3 4745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.