Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877433 | 0.84 | ALDH3A1 (0.40) | L3MBTL1HTTALDH3A1NOD1POLB | |
| SCHEMBL7678499 | 0.74 | RAPGEF4 (0.56) | L3MBTL1HTTALDH3A1NOD1POLB | |
| SCHEMBL29888784 | 0.70 | HTR6 (0.45) | HTTNOD1RAPGEF4ALDH1A1NOD2 | |
| SCHEMBL29888826 | 0.70 | RAPGEF4 (0.43) | L3MBTL1RAPGEF4HTR1ADRD2HTR2A | |
| SCHEMBL30877263 | 0.70 | ALDH3A1 (0.42) | L3MBTL1HTTALDH3A1NOD1POLB | |
| SCHEMBL28154364 | 0.69 | RAPGEF4 (0.48) | L3MBTL1RAPGEF4KDM4EUBE2NHTR1A | |
| SCHEMBL21590225 | 0.68 | RAPGEF4 (0.52) | L3MBTL1HTTALDH3A1NOD1POLB | |
| SCHEMBL28458237 | 0.68 | RAPGEF4 (0.52) | L3MBTL1HTTALDH3A1NOD1POLB | |
| SCHEMBL30977550 | 0.68 | CYP2A6 (0.50) | L3MBTL1POLBRAPGEF4ALDH1A1GBA1 | |
| SCHEMBL28487419 | 0.68 | RAPGEF4 (0.49) | L3MBTL1POLBRAPGEF4GAAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |