Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6109500 | 0.74 | FAAH (0.39) | FAAHEPHX2NPSR1HTTKDM4E | |
| SCHEMBL15656865 | 0.72 | SIGMAR1 (0.40) | FAAHEPHX2NPSR1MEN1KMT2A | |
| SCHEMBL4084097 | 0.71 | CYP11B1 (0.38) | EPHX2NPSR1MEN1KMT2AHTT | |
| SCHEMBL4433788 | 0.71 | MEN1 (0.43) | FAAHEPHX2NPSR1MEN1KMT2A | |
| SCHEMBL15275551 | 0.70 | SIGMAR1 (0.39) | FAAHEPHX2NPSR1MEN1KMT2A | |
| SCHEMBL27742096 | 0.70 | FAAH (0.34) | FAAHEPHX2NPSR1HTTKDM4E | |
| SCHEMBL30402889 | 0.70 | SIGMAR1 (0.39) | FAAHEPHX2NPSR1MEN1KMT2A | |
| SCHEMBL15657435 | 0.68 | MEN1 (0.39) | FAAHEPHX2NPSR1MEN1KMT2A | |
| SCHEMBL30137705 | 0.67 | LMNA (0.36) | NPSR1MEN1KMT2AHTTKDM4E | |
| SCHEMBL22714067 | 0.67 | LMNA (0.36) | NPSR1MEN1KMT2AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198471-B2 | 2, 2′-bis (dialkylphosphino) biphenyl compound, production method thereof, and metal complex comprising the compound as ligand | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2012-06-12 | — | — | US | disclosed |
| US-20100234626-A1 | 2, 2'-BIS (DIALKYLPHOSPHINO) BIPHENYL COMPOUND, PRODUCTION METHOD THEREOF, AND METAL COMPLEX COMPRISING THE COMPOUND AS LIGAND | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234626-A1 | 2, 2'-BIS (DIALKYLPHOSPHINO) BIPHENYL COMPOUND, PRODUCTION METHOD THEREOF, AND METAL COMPLEX COMPRISING THE COMPOUND AS LIGAND | BMPR1A, ADORA1, BMPR1B | FAAH 3039/4885EPHX2 1590/4885NPSR1 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.