Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817423 | 1.00 | MAPT (0.43) | MAPTALDH1A1GAATSHRTP53 | |
| SCHEMBL10926304 | 1.00 | MAPT (0.43) | MAPTALDH1A1GAATSHRTP53 | |
| SCHEMBL5799083 | 0.84 | MAPT (0.45) | MAPTALDH1A1GAATSHRTP53 | |
| SCHEMBL6055231 | 0.83 | MAPT (0.41) | MAPTALDH1A1GAATSHRTP53 | |
| SCHEMBL7066918 | 0.83 | AOC3 (0.44) | MAPTALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL3893551 | 0.81 | MAPT (0.41) | MAPTALDH1A1GAATSHRTP53 | |
| SCHEMBL5227537 | 0.81 | GABRA1 (0.46) | MAPTALDH1A1GAATSHRTP53 | |
| SCHEMBL27564004 | 0.80 | MAPT (0.42) | MAPTALDH1A1GAATSHRTP53 | |
| SCHEMBL13486824 | 0.79 | CHEK1 (0.46) | MAPTALDH1A1GAATSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2866667 | 0.79 | GABRA1 (0.44) | MAPTALDH1A1GAATSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233847-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GenKyoTex Suisse SA (CH) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016098005-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2016-06-23 | — | — | WO | disclosed |
| US-9321045-B2 | Catalyst and process for synthesising the same | THE UNIVERSITY OF WARWICK (GB) | 2016-04-26 | — | — | US | disclosed |
| US-20150290634-A1 | Catalyst and Process for Synthesising the Same | THE UNIVERSITY OF WARWICK (GB) | 2015-10-15 | — | — | US | disclosed |
| US-7799952-B2 | Stereoselective method for the production of (R)-Dimepranol | RATIOPHARM GMBH (DE) | 2010-09-21 | — | — | US | disclosed |
| US-20090149677-A1 | Stereoselective Method for the Production of (R)-Dimepranol | RATIOPHARM GMBH (DE) | 2009-06-11 | — | — | US | disclosed |
| US-7507827-B2 | Stereoselective method for the production of Clopidogrel | RATIOPHARM GMBH (DE) | 2009-03-24 | — | — | US | disclosed |
| US-20070219166-A1 | Stereoselective Method for the Production of Clopidogrel | RATIOPHARM GMBH (DE) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150290634-A1 | Catalyst and Process for Synthesising the Same | CBR3, SPR, RNF5 | MAPT 1869/4885ALDH1A1 2244/4885GAA 4488/4885 |
| US-20090149677-A1 | Stereoselective Method for the Production of (R)-Dimepranol | ADH5, ADH1A, ADH1C | MAPT 3745/4885ALDH1A1 222/4885GAA 2362/4885 |
| US-20070219166-A1 | Stereoselective Method for the Production of Clopidogrel | CYP2C19, ADH1C, TBXA2R | MAPT 4834/4885ALDH1A1 33/4885GAA 1963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.