SCHEMBL30924172

SCHEMBL30924172

NC(=O)OCc1ccc2ccccc2c1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
SLC1A1 P43005 1/20 0.54
RAB9A P51151 2/20 0.47
CYP1A2 P05177 2/20 0.47
NPC1 O15118 2/20 0.47
MAPT P10636 2/20 0.47
CYP2A6 P11509 1/20 0.46
ALOX5 P09917 1/20 0.45
TACR1 P25103 1/20 0.45
MRGPRX4 Q96LA9 1/20 0.44
CACNA1B Q00975 1/20 0.44
PPARG P37231 1/20 0.43
PPARD Q03181 1/20 0.43
PPARA Q07869 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
HTR2B P41595 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1321228 1.00 SLC1A3 (0.54) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL28936084 0.85 CYP1A2 (0.54) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL796762 0.85 CYP1A2 (0.52) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL6443298 0.84 SLC1A3 (0.55) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL6443296 0.84 SLC1A3 (0.51) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL2005477 0.83 CYP1A2 (0.53) SLC1A3SLC1A2SLC1A1CYP1A2NPC1
SCHEMBL729692 0.82 ALDH1A1 (0.61) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL487508 0.82 ALDH1A1 (0.61) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL6406854 0.82 SLC1A3 (0.50) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL6910495 0.82 SLC1A3 (0.50) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119365465-A Condensed ring compound, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2025-01-24 CN disclosed
CN-118139855-A 1, 4-Oxaazepane derivatives and their use 北京加科思新药研发有限公司 2024-06-04 CN disclosed