Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28936084 | 0.85 | CYP1A2 (0.54) | SLC1A3SLC1A2SLC1A1RAB9ACYP1A2 | |
| SCHEMBL6443298 | 0.84 | SLC1A3 (0.55) | SLC1A3SLC1A2SLC1A1RAB9ACYP1A2 | |
| SCHEMBL6443296 | 0.84 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1RAB9ACYP1A2 | |
| SCHEMBL10356778 | 0.83 | RAB9A (0.47) | SLC1A3SLC1A2SLC1A1RAB9ACYP1A2 | |
| SCHEMBL5215830 | 0.83 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1RAB9ACYP1A2 | |
| SCHEMBL729692 | 0.82 | ALDH1A1 (0.61) | SLC1A3SLC1A2SLC1A1RAB9ACYP1A2 | |
| SCHEMBL30924172 | 0.82 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1RAB9ACYP1A2 | |
| SCHEMBL1321228 | 0.82 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1RAB9ACYP1A2 | |
| SCHEMBL487508 | 0.82 | ALDH1A1 (0.61) | SLC1A3SLC1A2SLC1A1RAB9ACYP1A2 | |
| SCHEMBL2001872 | 0.82 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171195-A1 | P2X7 antagonists for treating neuropathic pain | ABBOTT LABORATORIES | 2005-08-04 | — | — | US | claimed |
| US-20050171195-A1 | P2X7 antagonists for treating neuropathic pain | ABBOTT LABORATORIES | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171195-A1 | P2X7 antagonists for treating neuropathic pain | P2RX3, P2RX7, P2RX1 | SLC1A3 392/4885SLC1A2 207/4885SLC1A1 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.