Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.59 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | RARB | P10826 | 1/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.59 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL597882 | 1.00 | PTGS2 (0.63) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL349312 | 1.00 | PTGS2 (0.63) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| Water SCHEMBL30850045 | 0.98 | PTGS2 (0.61) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL18205083 | 0.98 | PTGS2 (0.61) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| Hydrochloric Acid SCHEMBL5846561 | 0.98 | PTGS2 (0.61) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL22228509 | 0.94 | PTGS2 (0.68) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| Formic Acid SCHEMBL30236894 | 0.92 | PTGS2 (0.55) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL59197 | 0.90 | PTGS2 (0.74) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| Water SCHEMBL30850051 | 0.88 | PTGS2 (0.52) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| Trifluoroacetic Acid SCHEMBL30237172 | 0.88 | AKR1C3 (0.57) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111349681-A | Method for splitting 2- (4-methylphenyl) propionic acid enantiomer by using immobilized lipase to catalyze ester hydrolysis kinetics | 湖南理工学院 | 2020-06-30 | — | — | CN | claimed |
| EP-4249470-A1 | METHOD FOR PREPARING ALPHA-AMINO ACIDS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2023-09-27 | — | — | EP | disclosed |
| CN-112526013-B | Method for detecting concentration of related substances in ibuprofen medicament by using ultra-high liquid chromatography | 人福普克药业（武汉）有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-108642119-B | Method for resolution of 2- (4-methylphenyl) propionic acid enantiomer by stereoselective enzyme catalytic esterification | 湖南理工学院 | 2021-09-07 | — | — | CN | disclosed |
| CN-111349681-A | Method for splitting 2- (4-methylphenyl) propionic acid enantiomer by using immobilized lipase to catalyze ester hydrolysis kinetics | 湖南理工学院 | 2020-06-30 | — | — | CN | disclosed |
| EP-2251316-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ESTER AND METHOD FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID | TOKYO UNIV OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2018-02-21 | — | — | EP | disclosed |
| WO-2014198594-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-12-18 | — | — | WO | disclosed |
| US-20140135520-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBOXYLIC ACID ESTER | Tokyo University of Science Educational Foundation Administration Organization (JP) | 2014-05-15 | — | — | US | disclosed |
| EP-2719679-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBOXYLIC ACID ESTER | Tokyo University Of Science Educational Foundation Administrative Organization (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-2251316-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ESTER AND METHOD FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID | Tokyo University Of Science Educational Foundation Administrative Organization (JP) | 2010-11-17 | — | — | EP | disclosed |
| US-20100234610-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ESTER AND METHOD FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234610-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ESTER AND METHOD FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID | ACADM, ADH5, ALDH7A1 | PTGS2 1254/4885PTGS1 820/4885AKR1C3 462/4885 |
| US-20140135520-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBOXYLIC ACID ESTER | ALDH1A2, ADH1C, ADH1A | PTGS2 2021/4885PTGS1 2304/4885AKR1C3 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.