Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | UQCRB | P14927 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 4/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30936634 | 0.84 | L3MBTL1 (0.46) | L3MBTL1UQCRBHSD17B2MCOLN2ALDH1A1 | |
| SCHEMBL30936692 | 0.82 | MCOLN2 (0.53) | L3MBTL1UQCRBHSD17B2MCOLN2ALDH1A1 | |
| SCHEMBL30936704 | 0.82 | MCOLN2 (0.43) | L3MBTL1MCOLN2ELANEPRTN3ALDH1A1 | |
| SCHEMBL13311031 | 0.79 | PKM (0.57) | L3MBTL1ALDH1A1GAALMNAHPGD | |
| SCHEMBL23057210 | 0.78 | KEAP1 (0.51) | L3MBTL1MCOLN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL29978580 | 0.78 | KEAP1 (0.51) | L3MBTL1MCOLN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL30936639 | 0.77 | LIMK2 (0.51) | — | |
| SCHEMBL29772899 | 0.75 | LIMK2 (0.48) | — | |
| SCHEMBL24628229 | 0.75 | LIMK2 (0.48) | — | |
| SCHEMBL23057336 | 0.75 | MCOLN2 (0.47) | L3MBTL1MCOLN2ALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250340510-A1 | Substituted Phenylbenzenesulfonamide Derivatives and Uses Thereof | NINE SQUARE THERAPEUTICS CORPORATION (US) | 2025-11-06 | — | — | US | disclosed |
| EP-4608389-A2 | SUBSTITUTED PHENYLBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | Nine Square Therapeutics Corporation (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024092235-A2 | SUBSTITUTED PHENYLBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | NINE SQUARE THERAPEUTICS CORPORATION (US) | 2024-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250340510-A1 | Substituted Phenylbenzenesulfonamide Derivatives and Uses Thereof | TRPM2, TRPM6, TRPM5 | L3MBTL1 2204/4885UQCRB 2846/4885HSD17B2 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.