SCHEMBL3094346

SCHEMBL3094346

C1=Cc2c(c3ccccc3c3ccccc23)OC1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 7/20 0.37
CYP1A1 P04798 6/20 0.37
CYP1B1 Q16678 5/20 0.37
CYP2B6 P20813 3/20 0.37
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29809919 1.00 CYP1A2 (0.37) CYP1A2CYP1A1CYP1B1CYP2B6CA1
SCHEMBL7534013 0.76 MAOA (0.41) CYP1A2CYP1A1CYP1B1CYP2B6KMT2A
SCHEMBL4536799 0.74 CYP2B6 (0.47) CYP1A2CYP1A1CYP1B1CYP2B6KMT2A
SCHEMBL1010575 0.73 TNKS (0.37) CYP1A2CYP1A1CYP1B1CYP2B6KMT2A
SCHEMBL20623232 0.73 MAPT (0.38) KMT2A
SCHEMBL3624225 0.73 CYP2B6 (0.40) CYP1A2CYP1A1CYP1B1CYP2B6KMT2A
SCHEMBL29384225 0.73 TRPM4 (0.43) CYP1A2CYP1A1CYP1B1CYP2B6CA1
SCHEMBL1063519 0.72 CA1 (0.36) CYP1A2CYP1A1CYP1B1CYP2B6CA1
SCHEMBL1011282 0.72 CA1 (0.36) CYP2B6CA1
SCHEMBL8234878 0.72 MAOA (0.41) CYP1A2CYP1A1CYP1B1CYP2B6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114031597-B Polysubstituted dibenzochromene compound and application thereof 江苏视科新材料股份有限公司 2023-08-01 CN claimed
CN-114031596-B Dibenzo chromene photochromic compound and application thereof 江苏视科新材料股份有限公司 2023-07-28 CN claimed
CN-114031598-B Preparation method of polysubstituted dibenzochromene compound 江苏视科新材料股份有限公司 2023-07-28 CN claimed
CN-114031599-B Preparation method of dibenzochromene photochromic compound 江苏视科新材料股份有限公司 2023-07-25 CN claimed
CN-114031594-B Dibenzo chromene compound and application thereof 江苏视科新材料股份有限公司 2023-06-20 CN claimed
CN-114057682-B Preparation method of dibenzochromene compound 江苏视科新材料股份有限公司 2023-06-20 CN claimed
CN-114031597-B Polysubstituted dibenzochromene compound and application thereof 江苏视科新材料股份有限公司 2023-08-01 CN disclosed
CN-114031597-B Polysubstituted dibenzochromene compound and application thereof 江苏视科新材料股份有限公司 2023-08-01 CN disclosed
CN-114031597-B Polysubstituted dibenzochromene compound and application thereof 江苏视科新材料股份有限公司 2023-08-01 CN disclosed
CN-114031598-B Preparation method of polysubstituted dibenzochromene compound 江苏视科新材料股份有限公司 2023-07-28 CN disclosed
CN-114031596-B Dibenzo chromene photochromic compound and application thereof 江苏视科新材料股份有限公司 2023-07-28 CN disclosed
CN-114031598-B Preparation method of polysubstituted dibenzochromene compound 江苏视科新材料股份有限公司 2023-07-28 CN disclosed
CN-114031598-B Preparation method of polysubstituted dibenzochromene compound 江苏视科新材料股份有限公司 2023-07-28 CN disclosed
US-8404869-B2 Phenanthrenequinone-based compound and pharmaceutical composition containing the same for the treatment or prevention of disease involving metabolic syndrome MAZENCE INC. (KR) 2013-03-26 US disclosed
US-20100234453-A1 PHARMACEUTICAL COMPOSITION CONTAINING PHENANTHRENEQUINONE-BASED COMPOUND FOR INTESTINE DELIVERY SYSTEM KT & G CO., LTD. (KR) 2010-09-16 US disclosed
US-20100137422-A1 NOVEL PHENANTHRENEQUINONE-BASED COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR THE TREATMENT OR PREVENTION OF DISEASE INVOLVING METABOLIC SYNDROME YUNGJIN PHARM. CO., LTD. (KR) 2010-06-03 US disclosed
EP-2137175-A1 NOVEL PHENANTHRENEQUINONE-BASED COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR THE TREATMENT OR PREVENTION OF DISEASE INVOLVING METABOLIC SYNDROME Mazence Inc. (KR) 2009-12-30 EP disclosed
EP-2094262-A1 PHARMACEUTICAL COMPOSITION CONTAINING PHENANTHRENEQUINONE-BASED COMPOUND FOR INTESTINE DELIVERY SYSTEM Mazence Inc. (KR) 2009-09-02 EP disclosed
WO-2008133441-A1 NOVEL PHENANTHRENEQUINONE-BASED COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR THE TREATMENT OR PREVENTION OF DISEASE INVOLVING METABOLIC SYNDROME MAZENCE INC. (KR) 2008-11-06 WO disclosed
WO-2008066296-A1 PHARMACEUTICAL COMPOSITION CONTAINING PHENANTHRENEQUINONE-BASED COMPOUND FOR INTESTINE DELIVERY SYSTEM MAZENCE INC. (KR) 2008-06-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234453-A1 PHARMACEUTICAL COMPOSITION CONTAINING PHENANTHRENEQUINONE-BASED COMPOUND FOR INTESTINE DELIVERY SYSTEM SLC10A2, SI, ABCB11 CYP1A2 134/4885CYP1A1 114/4885CYP1B1 144/4885
US-20100137422-A1 NOVEL PHENANTHRENEQUINONE-BASED COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR THE TREATMENT OR PREVENTION OF DISEASE INVOLVING METABOLIC SYNDROME CYP27A1, CYP46A1, PCSK9 CYP1A2 166/4885CYP1A1 47/4885CYP1B1 107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.