Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 5/20 | 0.34 |
| ▸ | METTL14 | Q9HCE5 | 5/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30920694 | 0.85 | MTNR1A (0.37) | ACACBMTNR1AMTNR1BMAPK1SMN1; SMN2 | |
| SCHEMBL27247644 | 0.85 | MTNR1A (0.39) | MTNR1AMTNR1BNAMPTLMNAMETTL3 | |
| SCHEMBL27246963 | 0.84 | RAB9A (0.40) | MTNR1AMTNR1BALDH1A1NPC1MAPT | |
| SCHEMBL30946086 | 0.84 | PARP15 (0.41) | ACACBMTNR1AMTNR1BMAPK1SMN1; SMN2 | |
| SCHEMBL27248294 | 0.84 | MAOA (0.40) | MTNR1AMTNR1BMAPK1LMNAMETTL3 | |
| SCHEMBL30920497 | 0.84 | NPC1 (0.34) | ACACBNAMPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL27246805 | 0.84 | NPC1 (0.34) | ACACBNAMPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL27247565 | 0.83 | MTNR1A (0.37) | MTNR1AMTNR1BNAMPTSMN1; SMN2METTL3 | |
| SCHEMBL27247600 | 0.83 | MTNR1A (0.40) | MTNR1AMTNR1BSMN1; SMN2METTL3METTL14 | |
| SCHEMBL30946112 | 0.83 | LMNA (0.46) | ACACBNAMPTMAPK1SMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199546-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | HERCULES CAPITAL, INC., AS AGENT | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199546-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | SLC6A19, SLC2A9, SLC6A3 | ACACB 2323/4885MTNR1A 158/4885MTNR1B 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.