Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19713871 | 0.82 | CYP1A2 (0.63) | ALDH1A1KDM4ECYP1A2CYP2C19CYP3A4 | |
| SCHEMBL20715535 | 0.82 | LMNA (0.57) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL17824285 | 0.82 | DRD2 (0.52) | ALDH1A1KDM4ECYP1A2CYP2C19CYP3A4 | |
| SCHEMBL17833385 | 0.82 | LMNA (0.60) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL19714100 | 0.79 | LMNA (0.73) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL30951936 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KDM4ECYP2C19LMNASMN1; SMN2 | |
| SCHEMBL19714116 | 0.77 | KDM4E (0.54) | ALDH1A1KDM4EMAPTLMNACYP2C9 | |
| Hydrochloric Acid SCHEMBL5119311 | 0.77 | MAPT (0.56) | MAPTMEN1KMT2A | |
| SCHEMBL18955316 | 0.77 | KDM4E (0.62) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL17824312 | 0.76 | RAB9A (0.64) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362184-A1 | PRO-SURVIVAL COMPOUNDS | HERIOT-WATT UNIVERSITY (GB) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362184-A1 | PRO-SURVIVAL COMPOUNDS | MCL1, MKI67, MORF4L1 | ALDH1A1 95/4885KDM4E 3457/4885CYP1A2 4708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.