Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.37 |
| ▸ | PDE4A | P27815 | 5/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.37 |
| ▸ | POLQ | O75417 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | ATF1 | P18846 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962863 | 0.89 | NFKB1 (0.42) | PIN1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30962582 | 0.86 | CHRNA7 (0.41) | PDE4BPDE4APDE4CPDE4DNFKB1 | |
| SCHEMBL30962872 | 0.84 | NFKB1 (0.39) | PIN1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30962625 | 0.84 | PDE4D (0.47) | DHODHPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30962815 | 0.80 | CHRNA7 (0.40) | PIN1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30962730 | 0.80 | POLB (0.46) | PDE4BPDE4APDE4CPDE4DNFKB1 | |
| SCHEMBL30962740 | 0.76 | CHRNA7 (0.38) | PIN1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30962894 | 0.76 | CHRNA7 (0.48) | PIN1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30962916 | 0.75 | GAA (0.46) | DHODHGAAXPO1NPC1 | |
| SCHEMBL30962629 | 0.74 | NFKB1 (0.44) | PIN1NFKB1ATF1XPO1JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |