Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | JUN | P05412 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962568 | 0.83 | NNMT (0.46) | NNMTPIN1SYKJUNNFKB1 | |
| SCHEMBL17673007 | 0.78 | PIN1 (0.56) | CNR1HTTPARP10PIN1PARP1 | |
| SCHEMBL5723638 | 0.78 | NFKB1 (0.39) | LMNATSHRJUNNFKB1NFKB2 | |
| SCHEMBL2232809 | 0.77 | CNR1 (0.41) | NNMTCNR1LMNAHTTPARP10 | |
| SCHEMBL24588213 | 0.77 | NFKB1 (0.51) | NNMTLMNASYKJUNNFKB1 | |
| SCHEMBL3909479 | 0.74 | JUN (0.54) | NNMTLMNAJUNNFKB1NFKB2 | |
| SCHEMBL21596337 | 0.74 | PIN1 (0.55) | PARP10PIN1SYKMEN1KMT2A | |
| SCHEMBL30422501 | 0.73 | MKNK1 (0.42) | NNMTPARP10MKNK1MKNK2SYK | |
| SCHEMBL22261319 | 0.73 | JAK3 (0.63) | LMNA | |
| SCHEMBL5021094 | 0.73 | NUDT1 (0.39) | HTTMKNK1MKNK2PIN1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |