Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATF1 | P18846 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962644 | 0.87 | JUN (0.41) | CHRNA7POLBNFKB1MAPTKMT2A | |
| SCHEMBL30962815 | 0.87 | CHRNA7 (0.40) | CHRNA7POLBATF1NFKB1PIN1 | |
| SCHEMBL30962730 | 0.86 | POLB (0.46) | CHRNA7POLBATF1NFKB1PDE4D | |
| SCHEMBL30962894 | 0.82 | CHRNA7 (0.48) | CHRNA7POLBATF1NFKB1PIN1 | |
| SCHEMBL30962582 | 0.81 | CHRNA7 (0.41) | CHRNA7POLBATF1NFKB1PDE4D | |
| SCHEMBL30962627 | 0.80 | PDE4A (0.43) | CHRNA7ATF1NFKB1PDE4DPDE4A | |
| SCHEMBL30962881 | 0.79 | NFKB1 (0.48) | POLBATF1NFKB1PDE4DPDE4A | |
| SCHEMBL30962863 | 0.77 | NFKB1 (0.42) | ATF1NFKB1PIN1PDE4DPDE4A | |
| SCHEMBL30962814 | 0.76 | PIN1 (0.45) | ATF1NFKB1PIN1PDE4DPDE4A | |
| SCHEMBL16649261 | 0.75 | PIN1 (0.50) | CHRNA7POLBPIN1PDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |