Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 5/20 | 0.54 |
| ▸ | HTR2A | P28223 | 4/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964244 | 0.79 | ALDH1A1 (0.61) | KMT2ATSHRALDH1A1MEN1GAA | |
| SCHEMBL30964277 | 0.77 | ALDH1A1 (0.59) | KMT2ATSHRALDH1A1MEN1GAA | |
| SCHEMBL17946113 | 0.77 | DRD2 (0.73) | KMT2ATSHRALDH1A1NPSR1MEN1 | |
| SCHEMBL17946603 | 0.76 | CACNA1G (0.72) | KMT2ATSHRALDH1A1NPSR1MEN1 | |
| SCHEMBL30964256 | 0.74 | HTR1A (0.56) | KMT2ANPSR1MEN1GAADRD2 | |
| SCHEMBL14494939 | 0.74 | HTR1A (0.58) | KMT2AALDH1A1MEN1DRD2HTR2A | |
| SCHEMBL14494938 | 0.72 | HTR1A (0.58) | KMT2AALDH1A1DRD2HTR2AHTR1A | |
| SCHEMBL1577875 | 0.72 | KMT2A (0.70) | KMT2ATSHRMEN1GAADRD2 | |
| SCHEMBL22303317 | 0.71 | DRD2 (0.60) | DRD2HTR2AHTR1ADRD4DRD3 | |
| SCHEMBL22302903 | 0.71 | DRD2 (0.60) | DRD2HTR2AHTR1ADRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118121699-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |