SCHEMBL30964331

SCHEMBL30964331

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nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GRIN2D O15399 1/20 0.44
▸ GRIN3B O60391 1/20 0.44
▸ GRIN1 Q05586 1/20 0.44
▸ GRIN2A Q12879 1/20 0.44
▸ GRIN2B Q13224 1/20 0.44
▸ GRIN2C Q14957 1/20 0.44
▸ GRIN3A Q8TCU5 1/20 0.44
▸ RXFP1 Q9HBX9 1/20 0.42
▸ BACE1 P56817 1/20 0.41
▸ TASP1 Q9H6P5 1/20 0.41
▸ REN P00797 1/20 0.40
▸ CTSD P07339 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30964328 0.91 GRIN2D (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30964326 0.88 GRIN2D (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30512699 0.85 GRIN2D (0.52) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29800882 0.84 GRIN2D (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29827042 0.84 BACE1 (0.44) RXFP1BACE1TASP1
Gigiltvil SCHEMBL30741431 0.84 CTSD (0.46) RENCTSD
SCHEMBL38656413 0.84 TASP1 (0.45) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL31462106 0.83 CTSB (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30570971 0.83 GRIN2D (0.55) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30437164 0.83 RXFP1 (0.49) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250115874-A1 Compositions And Methods For Making And Using Atherosclerotic Nanomatrix Vascular Sheets UAB RESEARCH FOUNDATION 2025-04-10 — — US disclosed
US-20240218017-A1 PEPTIDE AMPHIPHILES WITH MODIFIED DEGRADING SEQUENCES AND METHODS OF USE THEREOF Endomimetics LLC 2024-07-04 — — US disclosed
US-20240199698-A1 PEPTIDE AMPHIPHILE COMPOSITIONS AND METHODS OF USE THEREOF Endomimetics LLC 2024-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240218017-A1 PEPTIDE AMPHIPHILES WITH MODIFIED DEGRADING SEQUENCES AND METHODS OF USE THEREOF ABHD16A, LIPG, POLQ GRIN2D 2735/4885GRIN3B 1595/4885GRIN1 1805/4885
US-20240199698-A1 PEPTIDE AMPHIPHILE COMPOSITIONS AND METHODS OF USE THEREOF PLD4, NGLY1, VIP GRIN2D 1679/4885GRIN3B 690/4885GRIN1 990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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